Cannabidiol is the medical extract from the cannabis plant that helps with pain relief. The cannabis plant is grown using sunlight, water, carbon dioxide and oxygen.
Lewis Structure of CBD
(All the carbons have a hybridization of sp3, no chiral carbons, and there are no delocalized pi
bonds)
The area with the most positive charges are in the hexagon’s of carbons. The negative areas of
The longest bonds are between the carbons and hydrogens. The shortest bonds would be between
the double bonded carbons. The longest bond is the weakest bond, and the shortest bond is the
strongest.
By what route is the drug taken?
Cannabidiol can be taken in a couple various ways. The cannabidiol can be made into an edible or a beverage and taken orally. The plant can also be smoked and rubbed on your skin topically to relieve pain as well.
Where does the drug need to go in your body to do its job?
Cannabidiol has very little affinity for the two cannabinoid receptors, however it does modulate several other receptors and ion channels within the cell. At high concentrations, CBD activates the 5-HT1A serotonin receptor, conferring anti-anxiety, anti-pain perception, and anti-nausea to name a few effects. CBD also binds to TRPV1 which is an ion channel that mediates the effects of a wide range of medicinal herbs. This particular ion channel influences pain perception.
The drug enters into the blood stream and uses hydrogen bonding and london dispersion forces to cross cell membranes.
Once in the cell membranes the polar parts of the molecule bind the receptors in the cell, which are found in the parts of the molecule containing the oxygen atoms.
The duration of the effects is roughly 2-5 hours depending on dosage. The molecules stay in your blood stream for roughly 3 weeks, but ones metabolism plays a heavy influence on how long it stays in the body.
Nice and sweet article. I love edibles in Canada with CBD. But what is the london dispersion force exactly?