{"id":86,"date":"2018-12-04T09:02:30","date_gmt":"2018-12-04T09:02:30","guid":{"rendered":"https:\/\/sites.sandiego.edu\/meet-your-medicine\/?p=86"},"modified":"2018-12-13T00:02:59","modified_gmt":"2018-12-13T00:02:59","slug":"hydrocodone","status":"publish","type":"post","link":"https:\/\/sites.sandiego.edu\/meet-your-medicine\/2018\/12\/04\/hydrocodone\/","title":{"rendered":"Hydrocodone"},"content":{"rendered":"<div id=\"wpwrap\">\n<div id=\"wpcontent\">\n<div id=\"wpbody\" role=\"main\">\n<div id=\"wpbody-content\">\n<div class=\"wrap\">\n<form id=\"post\" action=\"post.php\" method=\"post\" name=\"post\">\n<div id=\"poststuff\">\n<div id=\"post-body\" class=\"metabox-holder columns-2\">\n<div id=\"post-body-content\">\n<div id=\"postdivrich\" class=\"postarea wp-editor-expand\">\n<div id=\"wp-content-wrap\" class=\"wp-core-ui wp-editor-wrap tmce-active has-dfw\" style=\"padding-top: 55px\">\n<div id=\"wp-content-editor-tools\" class=\"wp-editor-tools hide-if-no-js\">\n<h3 id=\"wp-content-media-buttons\" class=\"wp-media-buttons\">Derive<\/h3>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/form>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p><b>Pain-relieving drugs either naturally derived from poppy flowers or lab-made, semi-synthetic substitutes.<\/b><\/p>\n<h3>Design<\/h3>\n<h4>The Hydrocodone Structure<\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-125\" src=\"http:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/final-draft-287x300.jpg\" alt=\"\" width=\"287\" height=\"300\" srcset=\"https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/final-draft-287x300.jpg 287w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/final-draft-768x803.jpg 768w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/final-draft-980x1024.jpg 980w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/final-draft-600x627.jpg 600w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/final-draft.jpg 1126w\" sizes=\"auto, (max-width: 287px) 100vw, 287px\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>Hybridization and Circled Chiral atoms are shown in the structure<\/p>\n<h4>Space-Filling<\/h4>\n<div id=\"attachment_93\" style=\"width: 310px\" class=\"wp-caption alignnone\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-93\" class=\"size-medium wp-image-93\" src=\"http:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/F0047107-Hydrocodone_drug_molecule-300x225.jpg\" alt=\"\" width=\"300\" height=\"225\" srcset=\"https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/F0047107-Hydrocodone_drug_molecule-300x225.jpg 300w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/F0047107-Hydrocodone_drug_molecule-768x576.jpg 768w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/F0047107-Hydrocodone_drug_molecule-600x450.jpg 600w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/F0047107-Hydrocodone_drug_molecule.jpg 800w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><p id=\"caption-attachment-93\" class=\"wp-caption-text\">Hydrocodone, molecular model. Synthetic opioid derived from codeine and thebaine. Orally active narcotic analgesic and antitussive. Atoms are represented as spheres and are color-coded: carbon (grey), hydrogen (white), nitrogen (blue) and oxygen (red).<\/p><\/div>\n<h3>Delivery<\/h3>\n<h4>The Route Taken<\/h4>\n<p><b>Orally, Primarily tablets and capsules.<\/b><\/p>\n<h4>Destination in the Body<\/h4>\n<p><b>It need to be able to reach the stomach and into the digestive system for it to be absorbed thoroughly, then the chemicals need to be able to get the the nerve in order to inhibit the enzyme\u2019s active site responsible of creating the feeling of pain.<\/b><\/p>\n<h4>Intermolecular Forces<\/h4>\n<p><strong>Hydrogen Bonding<\/strong><\/p>\n<h4>How it Functions At Destination<\/h4>\n<p><b> They work by attaching to particular sites in the brain called opioid receptors, which carry messages to the brain. The message the brain receives is changed, so that pain is no longer perceived as painful. <\/b><\/p>\n<h4>The Chemical Properties<\/h4>\n<p><b>\u201cWhen cells in your body are injured or damaged, they release chemicals called prostaglandins\u2026The special nerve endings that sense pain are very sensitive to this chemical. When prostaglandin is released, the nerve endings respond to it by picking up and transmitting the pain and injury messages through the nervous system to the brain&#8230;When you take a pain reliever&#8230;it keeps injured or damaged cells from making and releasing prostaglandin. When the cells don&#8217;t release this chemical, it means that the brain won&#8217;t get the pain message as quickly or clearly\u201d (<\/b><a href=\"https:\/\/www.nemours.org\/welcome.html\"><b>Mary L. Gavin, MD<\/b><\/a><b> 2018). <\/b><\/p>\n<p>https:\/\/kidshealth.org\/en\/kids\/ibupro.html<\/p>\n<h3>Destruction<\/h3>\n<h4>Lifetime<\/h4>\n<p><strong>Four to Six Hours<\/strong><\/p>\n<h4>Oxidation<\/h4>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-medium wp-image-126\" src=\"http:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/IMG-2851-300x219.jpg\" alt=\"\" width=\"300\" height=\"219\" srcset=\"https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/IMG-2851-300x219.jpg 300w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/IMG-2851-768x562.jpg 768w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/IMG-2851-1024x749.jpg 1024w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/IMG-2851-600x439.jpg 600w, https:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/IMG-2851.jpg 1852w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/p>\n<h4>Excretion<\/h4>\n<p><strong>Excreted through Urinary Tract<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Derive Pain-relieving drugs either naturally derived from poppy flowers or lab-made, semi-synthetic substitutes. Design The Hydrocodone Structure &nbsp; Hybridization and Circled Chiral atoms are shown in the structure Space-Filling Delivery The Route Taken Orally, Primarily tablets and capsules. Destination in <a class=\"more-link\" href=\"https:\/\/sites.sandiego.edu\/meet-your-medicine\/2018\/12\/04\/hydrocodone\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":682,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-86","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hydrocodone - Meet Your Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.sandiego.edu\/meet-your-medicine\/2018\/12\/04\/hydrocodone\/\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:locale\" content=\"en_US\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:type\" content=\"article\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:title\" content=\"Hydrocodone - Meet Your Medicine\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:description\" content=\"Derive Pain-relieving drugs either naturally derived from poppy flowers or lab-made, semi-synthetic substitutes. 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