{"id":109,"date":"2018-12-05T07:46:28","date_gmt":"2018-12-05T07:46:28","guid":{"rendered":"https:\/\/sites.sandiego.edu\/meet-your-medicine\/?p=109"},"modified":"2018-12-05T07:46:28","modified_gmt":"2018-12-05T07:46:28","slug":"cbd-nate-and-kevin","status":"publish","type":"post","link":"https:\/\/sites.sandiego.edu\/meet-your-medicine\/2018\/12\/05\/cbd-nate-and-kevin\/","title":{"rendered":"CBD-Nate and Kevin"},"content":{"rendered":"<p>Cannabidiol is the medical extract from the cannabis plant that helps with pain relief. The cannabis plant is grown using sunlight, water, carbon dioxide and oxygen.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>Lewis Structure of CBD<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-110\" src=\"http:\/\/sites.sandiego.edu\/meet-your-medicine\/files\/2018\/12\/IMG_0481-300x225.jpg\" alt=\"\" width=\"296\" height=\"225\" \/><\/p>\n<p>(All the carbons have a hybridization of sp<sup>3<\/sup>, no chiral carbons, and there are no delocalized pi<\/p>\n<p>bonds)<\/p>\n<p>The area with the most positive charges are in the hexagon\u2019s of carbons. The negative areas of<\/p>\n<p>The longest bonds are between the carbons and hydrogens. The shortest bonds would be between<\/p>\n<p>the double bonded carbons. The longest bond is the weakest bond, and the shortest bond is the<\/p>\n<p>strongest.<\/p>\n<p>&nbsp;<\/p>\n<p>By what route is the drug taken?<\/p>\n<p>Cannabidiol can be taken in a couple various ways. The cannabidiol can be made into an edible or a beverage and taken orally. The plant can also be smoked and rubbed on your skin topically to relieve pain as well.<\/p>\n<p>Where does the drug need to go in your body to do its job?<\/p>\n<p>Cannabidiol has very little affinity for the two cannabinoid receptors, however it does modulate several other receptors and ion channels within the cell. At high concentrations, CBD activates the 5-HT1A serotonin receptor, conferring anti-anxiety, anti-pain perception, and anti-nausea to name a few effects. CBD also binds to TRPV1 which is an ion channel that mediates the effects of a wide range of medicinal herbs. This particular ion channel influences pain perception.<\/p>\n<p>&nbsp;<\/p>\n<p>The drug enters into the blood stream and uses hydrogen bonding and london dispersion forces to cross cell membranes.<\/p>\n<p>Once in the cell membranes the polar parts of the molecule bind the receptors in the cell, which are found in the parts of the molecule containing the oxygen atoms.<\/p>\n<p>&nbsp;<\/p>\n<p>The duration of the effects is roughly 2-5 hours depending on dosage. The molecules stay in your blood stream for roughly 3 weeks, but ones metabolism plays a heavy influence on how long it stays in the body.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cannabidiol is the medical extract from the cannabis plant that helps with pain relief. The cannabis plant is grown using sunlight, water, carbon dioxide and oxygen. &nbsp; &nbsp; Lewis Structure of CBD (All the carbons have a hybridization of sp3, <a class=\"more-link\" href=\"https:\/\/sites.sandiego.edu\/meet-your-medicine\/2018\/12\/05\/cbd-nate-and-kevin\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":682,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-109","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>CBD-Nate and Kevin - Meet Your Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/sites.sandiego.edu\/meet-your-medicine\/2018\/12\/05\/cbd-nate-and-kevin\/\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:locale\" content=\"en_US\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:type\" content=\"article\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:title\" content=\"CBD-Nate and Kevin - Meet Your Medicine\" class=\"yoast-seo-meta-tag\" \/>\n<meta property=\"og:description\" content=\"Cannabidiol is the medical extract from the cannabis plant that helps with pain relief. 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